Silver triflate catalyzed synthesis of 3-aminoalkylated indoles and evaluation of their antibacterial activities

Organic and Medicinal Chemistry Letters

Table 3 Zone of inhibition and MIC values of compounds against Gram positive and Gram negative bacteria

Compound	*E. coli*		*B. subtilis*		*S. aureus*
	Zone of inhibition (mm)	MIC (μg ml ^-1 )	Zone of inhibition (mm)	MIC (μg ml ^-1 )	Zone of inhibition (mm)	MIC (μg ml ^-1 )
4a	13	> 128	14	128	15	128
4b	16	64	16	64	10	> 128
4c	14	128	14	128	15	128
4d	13	> 128	14	128	13	128
4e	14	128	13	> 128	11	> 128
4f	15	128	12	> 128	10	> 128
4g	15	128	12	> 128	13	128
4h	13	> 128	14	128	11	> 128
4i	14	128	17	64	12	> 128
4j	13	128	15	128	12	> 128
4k	14	128	13	> 128	13	128
4l	15	64	12	> 128	14	128
4m	14	128	14	128	12	> 128
4n	14	128	14	128	13	128
4o	15	64	13	> 128	10	> 128
4p	13	128	14	128	12	> 128
4q	13	128	18	64	14	128
4r	16	64	17	64	14	128
Chloramphenicol	21	16	24	16	22	16