From: Cytotoxic and potent CYP1 inhibitors from the marine algae Cymopolia barbata
Compounds | CYP I isoforms | |||||
---|---|---|---|---|---|---|
 | 1A1 | 1A2 | 1B1 | 2 C19 | 2D6 | 3A4 |
PBQ1 | 0.39 ± 0.05 | 9.75 ± 0.0365 | 1.42 ± 0.14 | 0.08 ± 0.03 | 1.03 ± 0.40 | 5.07 ± 3.54 |
PBQ2 | 0.93 ± 0.26 | 10.55 ± 6.75 | 0.14 ± 0.04 | 0.12 ± 0.06 | 2.75 ± 0.96 | 8.31 ± 4.67 |