Organic and Medicinal Chemistry Letters

Table 1 In vitro anticancer activities against HeLa cell lines with compounds 7a–l ( n = 3)

From: Synthesis and evaluation of antitumor activities of novel chiral 1,2,4-triazole Schiff bases bearing γ-butenolide moiety

Compound	IC ₅₀(μM)	Compound	IC ₅₀(μM)
7a	19.7	7h	7.1
7b	4.4	7i	3.7
7c	11.6	7j	4.5
7d	11.2	7k	6.2
7e	6.8	7l	1.8
7f	5.1	DDP (Cisplatin)	2.6
7g	8.2

The IC₅₀ values represent the compound concentration (μM) required to inhibit tumor cell proliferation by 50%.

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