From: Synthesis of some novel 4-arylidene pyrazoles as potential antimicrobial agents
Compound a | Diameter of zone of inhibition in mm (MIC) b | |||
---|---|---|---|---|
B. subtilis | S. aureus | P. fluorescens | E. coli | |
4a | 28 ± 0.00 (0.04) | 26 ± 0.30 (0.4) | 14 ± 0.08 (400) | 14 ± 0.46 (400) |
4b | 20 ± 0.19 (4.0) | 24 ± 0.50 (0.4) | 15 ± 0.09 (400) | 14 ± 0.23 (400) |
4c | 16 ± 0.19 (40) | 24 ± 0.32 (0.4) | - | 14 ± 0.23 (400) |
4d | 16 ± 0.00 (40) | 12 ± 0.19 (400) | - | 14 ± 0.43 (400) |
4e | 12 ± 0.40 (400) | 16 ± 0.22 (40) | - | 20 ± 0.30 (4) |
4f | 24 ± 0.07 (0.4) | 20 ± 0.37 (4.0) | 14 ± 0.14 (400) | 18 ± 0.33 (40) |
4g | 14 ± 0.23 (400) | 12 ± 0.10 (400) | - | 20 ± 0.34 (4) |
5a | 28 ± 0.09 (0.04) | 30 ± 0.15 (0.04) | - | 20 ± 0.32 (4) |
5b | 16 ± 0.32 (40) | 25 ± 0.42 (0.4) | 16 ± 0.12 (40) | 14 ± 0.50 (400) |
5c | 14 ± 0.18 (400) | 22 ± 0.24 (40) |  | 18 ± 0.54 (40) |
5d | 22 ± 0.09 (4.0) | 22 ± 0.20 (4.0) | 16 ± 0.23 (40) | 20 ± 0.12 (4) |
5e | 14 ± 0.00 (400) | 16 ± 0.00 (40) | 25 ± 0.13 (0.4) | 18 ± 0.23 (40) |
5f | 12 ± 0.33 (400) | 16 ± 0.36 (40) | - | 16 ± 0.43 (40) |
5g | 14 ± 0.32 (400) | 12 ± 0.30 (400) | 14 ± 0.43 (400) | 20 ± 0.21 (4) |
Ciprofloxacin | 26 ± 0.025 (0.4) | 26 ± 0.45 (0.4) | 23 ± 0.42 (4.0) | 25 ± 0.44 (0.4) |