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Table 1 In vitro antibacterial activity of compounds 3 and 4

From: A facile iodine(III)-mediated synthesis of 3-(3-aryl-1-phenyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridines via oxidation of 2-((3-aryl-1-phenyl-1H-pyrazol-4-yl)methylene)-1-(pyridin-2-yl)hydrazines and their antimicrobial evaluations

Compounds

Diameter of growth of inhibition zone (mm)a

 

Staphylococcus aureus

Bacillus subtilis

Escherichia coli

Pseudomonas aeruginosa

3a

17.3

19.3

13.3

15.6

3b

16.6

17.3

-

13.2

3c

17.3

18.6

13.0

12.8

3d

18.6

19.3

14.3

15.0

3e

16.3

17.6

14.2

-

3f

16.3

17.6

-

13.5

3g

17.0

18.3

13.8

14.3

4a

22.6

24.6

19.6

17.3

4b

21.3

24.6

18.0

16.6

4c

20.3

21.6

16.3

15.3

4d

17.0

18.6

15.6

13.6

4e

15.5

16.0

-

16.2

4f

21.6

22.6

17.3

15.6

4g

18.6

19.3

14.6

15.3

Ciprofloxacin

27.6

26.3

25.0

25.3

  1. -, no activity
  2. aValues including diameter of the well (8 mm), are means of three replicates