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Table 1 Three component Strecker reaction using aniline (1 mmol), benzaldehyde (1 mmol) and TMSCN (1.2 mmol) in water (30 min): catalyst optimization

From: A truly green synthesis of α-aminonitriles via Strecker reaction

Entry

Catalyst

(10 mol %)

Yield (%)a

1

Indium

98

2

Indium (II) chloride

70

3

Indium (III) chloride

82

4

Indium (III) bromide

85

5

Indium selenide

62

6

Indium oxide

48

  1. aisolated yield