Scheme 1From: Design, synthesis and antimicrobial evaluation of novel 2-aryl-thiazolidin-4-one derivatives Synthetic routes to 4-substituted phenylamines (4a-c). Reagents and conditions: (a) NBS, benzoyl peroxide, CCl4, reflux, 4-5 h; (b) DBU, imidazole or 1,2,4-triazole or morpholine, THF, room temperature, 20-24 h; (c) SnCl2 2H2O, conc. HCl, 50-60°C, 5-6 h.Back to article page