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Table 4 In vitro antitubercular activity of compounds 7-12 by luciferase reporter phage assay method

From: In vitro microbiological evaluation of 1,1'-(5,5'-(1,4-phenylene)bis(3-aryl-1H-pyrazole-5,1-(4H,5H)-diyl))diethanones, novel bis acetylated pyrazoles

Compounds

M. Tuberculosis H37Rv

INH resistant M. tuberculosis

 

1.00 (μg/mL)

2.00 (μg/mL)

1.00 (μg/mL)

2.00 (μg/mL)

7

74

78

73

77

8

85

89

79

82

9

82

85

79

82

10

79

81

78

80

11

81

83

82

85

12

82

84

80

84

Isoniazid

99

99

90

96