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Organic and Medicinal Chemistry Letters

Table 2 Antibacterial and antifungal screening data of compounds 5a-l

From: Antimicrobial studies of unsymmetrical bis-1,2,3-triazoles

Compounds

Zone of inhibition (mm)

 

Antibacterial activities

Antifungal activities

 

B. subtilis (MTCC 619)

S. epidermidis (MTCC 435)

P. Vulgaris (MTCC 426)

P. aeruginosa (MTCC 424)

A. niger (MTCC1344)

P. chrysogenum (MTCC 947)

3a

08

09

10

12

-

10

3b

07

12

07

03

11

10

3c

-

11

10

12

10

10

3d

11

12

-

12

12

12

3e

12

10

13

10

10

16

3f

09

14

14

-

13

14

3g

12

-

08

11

12

09

3h

14

12

10

10

11

10

3i

10

12

-

09

13

12

3j

08

-

10

11

11

12

3k

07

16

11

11

12

13

3l

10

09

11

08

09

13

Control

-

-

-

-

-

-

Kenamycin

23

24

22

17

-

-

Flucanazole

-

-

-

 

18

14

  1. P. vulgaris, Proteus vulgaris; B. subtilis, Bacillus subtilis; S. epidermidis, Staphylococcus epidermidis; P. aeruginosa, Pseudomonas aeruginosa; DMSO, negative control; well diameter/vol.- 6 mm/50 μl; Kenamycin, standard for antibacterial activity. Flucanazole, standard for anti fungal activity.
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