Figure 4
From: Increase of leishmanicidal and tubercular activities using steroids linked to aminoquinoline
Effect of alkyne intermediate structures (3, 5 and 7) and aminoquinoline/steroid conjugates (12, 13 and 14) on intracellular amastigotes. Peritoneal macrophages previously infected with L. major promastigotes in the stationary growth phase were exposed to the compounds for 72 h. Results from two assays in duplicate are shown as percentage of growth inhibition in relation to untreated control. All results were significant (*** p < 0.0001).