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Organic and Medicinal Chemistry Letters

Table 3 Effect of α 2 -adrenoceptor antagonism on the antinociceptive effect of BISA in MO test

From: Attenuation of visceral nociception by α-bisabolol in mice: investigation of mechanisms

Group

Dose (mg/kg)

Specific behaviors

Normal

-

4.25 ± 1.77***

Vehicle

 

28.50 ± 4.00

BISA

50

1.29 ± 0.75***

BISA + yohibmine

50 + 2

5.75 ± 1.77***

  1. Values represent the mean ± S.E.M. of pain-related behaviors (licking of abdomen, stretching, abdominal retractions). ***p < 0.001 vs Vehicle (ANOVA, Student-Newman-Keul’s test).
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