Table 4 The antibacterial and antifungal activities of 1-phenyl-3(5-bromothiophen-2-yl)-5-(substitutedphenyl)-2-pyrazolines by disc diffusion method
Antibacterial activities | Antifungal activities | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Entry X | Zone of inhibition (mm) | Entry X | Zone of inhibition (mm) | ||||||||
S. aureus | E. coli | K. pneumoniae | S. typhi | Pseudomonas spp. | C. albicans | Mucor spp. | Rhizopus spp. | A. niger | |||
1 | H | 10 | 15 | 20 | 15 | 15 | 1 | 15 | 15 | 15 | 15 |
2 | 4-Br | 10 | 15 | 20 | 20 | 17 | 2 | 20 | 20 | 20 | 20 |
3 | 2-Cl | 15 | 15 | 15 | 5 | 5 | 3 | 15 | 15 | 15 | 15 |
4 | 4-Cl | 3 | 10 | 15 | 15 | 15 | 4 | 15 | 15 | 15 | 15 |
5 | 3,4-(OCH3)2 | 17 | 17 | 15 | 17 | 20 | 5 | 17 | 17 | 17 | 17 |
6 | 4-I | 15 | 17 | 20 | 17 | 10 | 6 | 17 | 17 | 17 | 17 |
7 | 4-OCH3 | 15 | 17 | 20 | 17 | 22 | 7 | 20 | 20 | 20 | 20 |
8 | 4-CH3 | 15 | 10 | 15 | 5 | 5 | 8 | 20 | 15 | 15 | 20 |
Cip | - | 17 | 17 | 20 | 22 | 15 | Ket | 15 | 15 | 15 | 15 |