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Table 2 Growth inhibition rates of HeLa cell lines with compounds 7a–l at different concentrations

From: Synthesis and evaluation of antitumor activities of novel chiral 1,2,4-triazole Schiff bases bearing γ-butenolide moiety

Compounds

  

Inhibition rates (%)

  
 

1.25 μM

2.5 μM

5 μM

10 μM

20 μM

7a

1.2

8.7

16.1

30.2

41.9

7b

26.2

30.2

53.8

65.2

85.7

7c

9.4

35.3

21.3

52.3

60.2

7d

17.9

11.0

34.8

47.7

65.5

7e

10.9

11.4

24.3

76.0

85.2

7f

10.3

27.4

56.9

73.4

85.1

7g

18.0

30.9

43.4

49.7

67.1

7h

8.3

14.3

40.7

77.5

71.7

7i

14.3

35.6

67.8

85.4

87.7

7j

24.0

32.5

54.1

67.6

81.2

7k

14.8

36.2

60.0

56.7

67.3

7l

47.5

45.4

74.1

88.6

90.0