Synthesis and screening of antibacterial and antifungal activity of 5-chloro-1,3-benzoxazol-2(3 h)-one derivatives

Organic and Medicinal Chemistry Letters

Table 3 Physical data of compounds

Compound code	Molecular formula	Molecular weight (g/mol)	Melting point (°C)	Yield (%w/w)	R _f value
P1A	C₇H₄ClNO₂	169.565	158	70.1	0.73
P2A	C₁₄H₁₀ClNO₂	259.68	169	78.4	0.84
P2B	C₁₄H₈Cl₃NO₂	328.577	176	56.9	0.68
P3A	C₁₄H₁₀N₄O₂	266.25	176	70.17	0.78
P3B	C₇H₄N₄O₂	176.13	168–172	94.23	0.74
P4A	C₁₆H₁₂N₄O₂	292.29	135	37.03	0.87
P4B	C₉H₆N₄O₂	202.169	179–183	42.15	0.54
P5A	C₂₀H₁₇N₃O₄S	395.43	195–200	65.79	0.71
P6A	C₂₁H₁₆N₂O₄	360.36	182	54.02	0.72