Skip to main content
Figure 5 | Organic and Medicinal Chemistry Letters

Figure 5

From: Cannabinoid receptor type 2 (CB2)-selective N-aryl-oxadiazolyl-propionamides: synthesis, radiolabelling, molecular modelling and biological evaluation

Figure 5

Model of the human cannabinoid receptor type 2. (a) Side view with the proposed transmembrane region shaded in grey. The protein is shown with the N-terminus at the top. (b) Top view from the extracellular space. The extracellular loops and the transmembrane helices are labelled to guide the reader. Only the residues forming the binding pocket are shown. The binding pocket identified by the Site Finder module of MOE (Chemical Computing Group Inc., Montreal, Canada) is shown as a surface with colour-coded features: H bonding (magenta), lipophilic (green), mild polar (blue).

Back to article page