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Table 3 Comparison of good MIC to IC50 values

From: Development of 4H-pyridopyrimidines: a class of selective bacterial protein synthesis inhibitors

Compound

MIC

IC50 μM

323338

+++

64.4

323339

+++

19.0

323340

+++

> 300

323341

+++

41.4

323342

+++

28.9

323343

+++

8.24

323344

+++

11.6

323365

+++

2.27

323366

+++

2.47

323367

+++

1.89

323370

+++

0.28

332054

+++

7.40

332058

+++

0.56