Synthesis and evaluation of substituted diphenyl-1,3,4-oxadiazole derivatives for central nervous system depressant activity

Organic and Medicinal Chemistry Letters

Table 6 Physico-chemical data of the synthesized compounds (IX-XII)

Compound	R	Molecular formula	Molecular weight	% Yield	m.p. (°C)	Rf^{solvent system}
IX	4-OH	C₇H₈N₂O₂	152.1	35.96	132-134	0.74^a
X	4-NO2	C₇H₇N₃O₃	181.15	58.01	148-150	0.82^a
XI	4-NH2	C₇H₉N₃O	151.17	29.16	142-144	0.75^a
XII	4-Cl	C₇H₇ClN₂O	170.60	53.13	156-158	0.77^a