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Table 1 Experimental logD coefficients of compounds 1 and 2

From: Radiofluorination and biological evaluation of N-aryl-oxadiazolyl-propionamides as potential radioligands for PET imaging of cannabinoid CB2 receptors

Compound

Reposil-Pur C18-AQa

Prodigy 5 μ C8 a

 

Isocratic

Gradient

Isocratic

1

4.21 ± 0.32

3.82 ± 0.10

3.86 ± 0.33

2

4.87 ± 0.36

4.35 ± 0.11

4.40 ± 0.35

  1. aExperiments performed with the respective reference compounds (n = 3 to 6).