Skip to main content

Table 2 Antifungal activities of the newly synthesized compounds

From: β-Keto esters from ketones and ethyl chloroformate: a rapid, general, efficient synthesis of pyrazolones and their antimicrobial, in silico and in vitro cytotoxicity studies

 

Trichophyton

Penicillium

A. flavus

A. fumigates

Compound number

    

1

25 (6.25)

23 (6.25)

26 (6.25)

27 (6.25)

2

24 (6.25)

25 (6.25)

24 (6.25)

26 (6.25)

3

29 (6.25)

26 (6.25)

27 (6.25)

28 (6.25)

4

21 (6.25)

22 (6.25)

26 (6.25)

22 (6.25)

5

16 (12.5)

17 (12.5)

12 (12.5)

14 (12.5)

6

17 (12.5)

17 (12.5)

11 (12.5)

15 (12.5)

7

24 (12.5)

21 (12.5)

21 (12.5)

20 (12.5)

8

26 (12.5)

24 (12.5)

27 (12.5)

23 (12.5)

9

27 (12.5)

25 (12.5)

28 (12.5)

22 (12.5)

10

20 (6.25)

22 (6.25)

17 (6.25)

22 (6.25)

11

21 (6.25)

21 (6.25)

23 (6.25)

21 (6.25)

13

22 (12.5)

25 (12.5)

27 (12.5)

23 (12.5)

14

30 (12.5)

22 (12.5)

26 (12.5)

24 (12.5)

15

26 (12.5)

23 (12.5)

27 (12.5)

23 (12.5)

17

31 (12.5)

25 (12.5)

28 (12.5)

23 (12.5)

19

25 (6.25)

24 (6.25)

27 (6.25)

24 (6.25)

20

28 (12.5)

29 (12.5)

25 (12.5)

25 (12.5)

21

31 (12.5)

28 (12.5)

27 (12.5)

24 (12.5)

23

29 (12.5)

27 (12.5)

26 (12.5)

21 (12.5)

24

23 (12.5)

26 (12.5)

23 (12.5)

25 (12.5)

25

21 (6.25)

20 (6.25)

21 (6.25)

23 (6.25)

26

25 (12.5)

22 (12.5)

27 (12.5)

28 (12.5)

Standard

27 (3.125)

23 (6.25)

27 (3.125)

26 (6.25)

  1. Zone of inhibition (mm), MIC (μg/mL) given in parenthesis and ciclopiroxolamine as standard.