Facile and efficient one-pot synthesis of benzimidazoles using lanthanum chloride

Organic and Medicinal Chemistry Letters

Table 3 Lanthanum chloride-catalyzed synthesis of benzimidazoles

Entry	Time (h)	Yields (%)
a	2.0	95
b	2.5	88
c	2.0	91
d	2.0	9.0
e	3.0	87
f	2.0	85
g	2.5	92
h	4.0	90
i	3.0	88
j	2.5	86
k	3.0	90
l	2.5	91
m	3.0	87
n	4.0	85
o	3.0	88
p	2.5	86
q	2.5	89

Entry	Time (h)	Yields (%)
a	2.0	95
b	2.5	88
c	2.0	91
d	2.0	9.0
e	3.0	87
f	2.0	85
g	2.5	92
h	4.0	90
i	3.0	88
j	2.5	86
k	3.0	90
l	2.5	91
m	3.0	87
n	4.0	85
o	3.0	88
p	2.5	86
q	2.5	89

Entry	Time (h)	Yields (%)
a	2.0	95
b	2.5	88
c	2.0	91
d	2.0	9.0
e	3.0	87
f	2.0	85
g	2.5	92
h	4.0	90
i	3.0	88
j	2.5	86
k	3.0	90
l	2.5	91
m	3.0	87
n	4.0	85
o	3.0	88
p	2.5	86
q	2.5	89

Entry	Time (h)	Yields (%)
a	2.0	95
b	2.5	88
c	2.0	91
d	2.0	9.0
e	3.0	87
f	2.0	85
g	2.5	92
h	4.0	90
i	3.0	88
j	2.5	86
k	3.0	90
l	2.5	91
m	3.0	87
n	4.0	85
o	3.0	88
p	2.5	86
q	2.5	89