Figure 3From: Design and synthesis of tetrahydrophthalimide derivatives as inhibitors of HIV-1 reverse transcriptaseRedocked mode of TNK 651 (3) (green) superimposed with the co-crystallized ligand (gray). Ligand is shown as stick model, and the amino acid residues interacting with the ligands are shown as line model. Hydrogen bond interaction (1.9 Å) with LYS 103 amino acid residue of reverse transcriptase is shown as dotted spheres. The rest of the protein is suppressed for clarification purposes.Back to article page