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Organic and Medicinal Chemistry Letters
Figure 4 | Organic and Medicinal Chemistry Letters

Figure 4

From: Design and synthesis of tetrahydrophthalimide derivatives as inhibitors of HIV-1 reverse transcriptase

Figure 4

Binding mode of standard drug efavirenz in the NNIBP of HIV-1 RT (1rt2). Ligand is shown as stick model, and the amino acid residues interacting with the ligands are shown as line model. Hydrogen bond interactions (1.8 Å) with LYS 101 amino acid residues of reverse transcriptase respectively are shown as dotted spheres. The rest of the protein is suppressed for clarification purposes.

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