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Table 3 HIV-1 RT inhibitory activity of synthesized compounds

From: Design and synthesis of tetrahydrophthalimide derivatives as inhibitors of HIV-1 reverse transcriptase

Serial number

Compound code

%RT inhibition

 

2 μM

20 μM

1

4a

NA

25

2

4b

NA

10

3

4c

NA

NA

4

4d

NA

NA

5

4e

NA

NA

6

4f

NA

20

7

4g

NA

15

8

4h

NA

NA

9

4i

NA

NA

10

4j

NA

NA

11

4k

NA

15

12

4l

NA

10

13

4m

NA

NA

14

4n

NA

NA

15

4o

NA

NA

16

4p

NA

NA

  1. NA indicates not active.