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Table 1 In vitro antibacterial activity and MIC of compounds 4 and 5 using agar well diffusion method

From: Synthesis of some novel 4-arylidene pyrazoles as potential antimicrobial agents

Compound a Diameter of zone of inhibition in mm (MIC) b
B. subtilis S. aureus P. fluorescens E. coli
4a 28 ± 0.00 (0.04) 26 ± 0.30 (0.4) 14 ± 0.08 (400) 14 ± 0.46 (400)
4b 20 ± 0.19 (4.0) 24 ± 0.50 (0.4) 15 ± 0.09 (400) 14 ± 0.23 (400)
4c 16 ± 0.19 (40) 24 ± 0.32 (0.4) - 14 ± 0.23 (400)
4d 16 ± 0.00 (40) 12 ± 0.19 (400) - 14 ± 0.43 (400)
4e 12 ± 0.40 (400) 16 ± 0.22 (40) - 20 ± 0.30 (4)
4f 24 ± 0.07 (0.4) 20 ± 0.37 (4.0) 14 ± 0.14 (400) 18 ± 0.33 (40)
4g 14 ± 0.23 (400) 12 ± 0.10 (400) - 20 ± 0.34 (4)
5a 28 ± 0.09 (0.04) 30 ± 0.15 (0.04) - 20 ± 0.32 (4)
5b 16 ± 0.32 (40) 25 ± 0.42 (0.4) 16 ± 0.12 (40) 14 ± 0.50 (400)
5c 14 ± 0.18 (400) 22 ± 0.24 (40)   18 ± 0.54 (40)
5d 22 ± 0.09 (4.0) 22 ± 0.20 (4.0) 16 ± 0.23 (40) 20 ± 0.12 (4)
5e 14 ± 0.00 (400) 16 ± 0.00 (40) 25 ± 0.13 (0.4) 18 ± 0.23 (40)
5f 12 ± 0.33 (400) 16 ± 0.36 (40) - 16 ± 0.43 (40)
5g 14 ± 0.32 (400) 12 ± 0.30 (400) 14 ± 0.43 (400) 20 ± 0.21 (4)
Ciprofloxacin 26 ± 0.025 (0.4) 26 ± 0.45 (0.4) 23 ± 0.42 (4.0) 25 ± 0.44 (0.4)
  1. MIC (μg/mL), minimum inhibitory concentration. Hyphens denote no activity. aThe concentration is 4.0 mg/mL. bThe values, including the diameter of the well (8 mm), are means of the three replicates.