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Table 1 Cytotoxic activity (IC 50 μM) of compounds 8a-i

From: Synthesis and biological evaluation of benzimidazole-linked 1,2,3-triazole congeners as agents

Compound A375 B-16 Colon-205 MCF-7 A-549
8a 2.7 - 1.3 3.2 0.1
8b 2.3 1.9 3.5 1.7 2.6
8c 1.6 16 0.12 1.9 -
8d - 4.7 8 - -
8e 2.1 - 1.3 0.3 1.8
8f 15 3.9 17 - -
8g 43 - 32 - 26
8h - - - 37 32
8i 27 10 21 - -
ADR 0.9 1.0 3.5 3.2 0.03