A truly green synthesis of α-aminonitriles via Strecker reaction

Organic and Medicinal Chemistry Letters

Table 4 Three component Strecker reaction using amines (1 mmol), carbonyl compounds (1 mmol) and TMSCN (1.2 mmol) in water in presence of indium (10 mol%)

Entry	Time (min)	Yield (%)^a	Ref.
1	30	98	[11]
2	75	93	[15]
3	75	79	[11]
4	45	86	[11]
5	60	88	[11]
6	75	91	[11]
7	90	94	[21]
8	75	95	[21]
9	90	97	[21]
10	45	98	[10]