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  1. Original article

    Sunlight-induced rapid and efficient biogenic synthesis of silver nanoparticles using aqueous leaf extract of Ocimum sanctum Linn. with enhanced antibacterial activity

    Nanotechnology is now regarded as a distinct field of research in modern science and technology with multifaceted areas including biomedical applications. Among the various approaches currently available for t...

    Goutam Brahmachari, Sajal Sarkar, Ranjan Ghosh, Soma Barman, Narayan C Mandal, Shyamal K Jash, Bubun Banerjee and Rajiv Roy

    Organic and Medicinal Chemistry Letters 2014 4:18

    Published on: 29 December 2014

  2. Original article

    An efficient heterogeneous catalyst (CuO@ARF) for on-water C-S coupling reaction: an application to the synthesis of phenothiazine structural scaffold

    Aryl sulfides have significant importance from biological and pharmaceutical aspects. Transition metal-catalyzed carbon-sulfur cross-coupling reaction represents an important tool for the synthesis of sulfides...

    Debasish Sengupta and Basudeb Basu

    Organic and Medicinal Chemistry Letters 2014 4:17

    Published on: 29 December 2014

  3. Short communication

    Synthesis of 2-cyclopropyl-3-(5-aryl-1H-pyrazol-3-yl)-1,8-naphthyridine

    1,8-Naphthyridine derivatives have attracted considerable attention because the 1,8-naphthyridine skeleton is present in many compounds that have been isolated from natural substances, with various biological ...

    Mallaiah Bucha, Laxminarayana Eppakayala, Thirumala Chary Maringanti, Giri Tharikoppula and Shashikala Kethireddy

    Organic and Medicinal Chemistry Letters 2014 4:16

    Published on: 21 December 2014

  4. Original article

    Effect of nano silver and silver nitrate on seed yield of (Ocimum basilicum L.)

    The aim of this study was to evaluate the effect of nano silver and silver nitrate on yield of seed in basil plant. The study was carried out in a randomized block design with three replications.

    Fatemeh Nejatzadeh-Barandozi, Fariborz Darvishzadeh and Ali Aminkhani

    Organic and Medicinal Chemistry Letters 2014 4:11

    Published on: 2 October 2014

  5. Short communication

    Cytotoxic compounds from Laurencia pacifica

    The current investigation sought to explore the nature of the secondary metabolites in the algae, Laurencia pacifica.

    Diana A Zaleta-Pinet, Ian P Holland, Mauricio Muñoz-Ochoa, J Ivan Murillo-Alvarez, Jennette A Sakoff, Ian A van Altena and Adam McCluskey

    Organic and Medicinal Chemistry Letters 2014 4:8

    Published on: 20 September 2014

  6. Short communication

    An expeditious green route toward 2-aryl-4-phenyl-1H-imidazoles

    Azaheterocycles are an important class of compounds because of their highly potent medicinal activities, and the imidazole subcategory is of special interest in regard to drug discovery research.

    Debasish Bandyopadhyay, Lauren C Smith, Daniel R Garcia, Ram N Yadav and Bimal K Banik

    Organic and Medicinal Chemistry Letters 2014 4:9

    Published on: 20 September 2014

  7. Original article

    The potential of anti-malarial compounds derived from African medicinal plants, part III: an in silico evaluation of drug metabolism and pharmacokinetics profiling

    Malaria is an endemic disease affecting many countries in Tropical regions. In the search for compound hits for the design and/or development of new drugs against the disease, many research teams have resorted...

    Pascal Amoa Onguéné, Fidele Ntie-Kang, James Ajeck Mbah, Lydia Likowo Lifongo, Jean Claude Ndom, Wolfgang Sippl and Luc Meva′a Mbaze

    Organic and Medicinal Chemistry Letters 2014 4:6

    Published on: 5 September 2014

  8. Original article

    Synthesis of phenylazonaphtol-β-D-O-glycosides, evaluation as substrates for beta-glycosidase activity and molecular studies

    Phenylazonaphtol-β-D-O-glycosides are alternative substrates for the detection of enzymatic activity of β-glycosidases which are involved in various important processes. These azoic compounds are currently exploi...

    Marco Brito-Arias, Carlos Aguilar-Lemus, Pamela B Hurtado-Ponce, Guadalupe Martínez-Barrón and Miguel Ibañez-Hernandez

    Organic and Medicinal Chemistry Letters 2014 4:2

    Published on: 17 May 2014

  9. Original article

    Radiofluorination and biological evaluation of N-aryl-oxadiazolyl-propionamides as potential radioligands for PET imaging of cannabinoid CB2 receptors

    The level of expression of cannabinoid receptor type 2 (CB2R) in healthy and diseased brain has not been fully elucidated. Therefore, there is a growing interest to assess the regional expression of CB2R in the b...

    Rodrigo Teodoro, Rareş-Petru Moldovan, Corinna Lueg, Robert Günther, Cornelius K Donat, Friedrich-Alexander Ludwig, Steffen Fischer, Winnie Deuther-Conrad, Bernhard Wünsch and Peter Brust

    Organic and Medicinal Chemistry Letters 2013 3:11

    Published on: 24 September 2013

  10. Original article

    Assessing the pharmacokinetic profile of the CamMedNP natural products database: an in silico approach

    Drug metabolism and pharmacokinetic (DMPK) assessment has come to occupy a place of interest during the early stages of drug discovery today. Computer-based methods are slowly gaining ground in this area and a...

    Fidele Ntie-Kang, James A Mbah, Lydia L Lifongo, Luc C Owono Owono, Eugene Megnassan, Luc Meva'a Mbaze, Philip N Judson, Wolfgang Sippl and Simon MN Efange

    Organic and Medicinal Chemistry Letters 2013 3:10

    Published on: 30 August 2013

  11. Original article

    Synthesis of some novel 4-arylidene pyrazoles as potential antimicrobial agents

    Pyrazole and pyrazolone motifs are well known for their wide range of biological activities such as antimicrobial, anti-inflammatory, and antitumor activities. The incorporation of more than one pharmacophore ...

    Poonam Khloya, Pawan Kumar, Arpana Mittal, Neeraj K Aggarwal and Pawan K Sharma

    Organic and Medicinal Chemistry Letters 2013 3:9

    Published on: 28 August 2013

  12. Original article

    Design and synthesis of tetrahydrophthalimide derivatives as inhibitors of HIV-1 reverse transcriptase

    Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are one of the key components in highly active anti-retroviral therapy because of their high specificity and less toxicity. NNRTIs inhibit reverse trans...

    Ashok Penta, Swastika Ganguly and Sankaran Murugesan

    Organic and Medicinal Chemistry Letters 2013 3:8

    Published on: 22 August 2013

    The Erratum to this article has been published in Organic and Medicinal Chemistry Letters 2013 3:12

  13. Original article

    Facile and efficient one-pot synthesis of benzimidazoles using lanthanum chloride

    We report the synthesis of benzimidazoles using lanthanum chloride as an efficient catalyst. One-pot synthesis of 2-substituted benzimidazole derivatives from o-phenylenediamine and a variety of aldehydes were de...

    Yekkirala Venkateswarlu, Sudhagani Ramesh Kumar and Panuganti Leelavathi

    Organic and Medicinal Chemistry Letters 2013 3:7

    Published on: 6 August 2013

  14. Original article

    β-Keto esters from ketones and ethyl chloroformate: a rapid, general, efficient synthesis of pyrazolones and their antimicrobial, in silico and in vitro cytotoxicity studies

    Pyrazolones are traditionally synthesized by the reaction of β-keto esters with hydrazine and its derivatives. There are methods to synthesize β-keto esters from esters and aldehydes, but these methods have ma...

    Ramasamy Venkat Ragavan, Kalavathi Murugan Kumar, Vijayaparthasarathi Vijayakumar, Sundaramoorthy Sarveswari, Sudha Ramaiah, Anand Anbarasu, Sivashanmugam Karthikeyan, Periyasamy Giridharan and Nalilu Suchetha Kumari

    Organic and Medicinal Chemistry Letters 2013 3:6

    Published on: 19 July 2013

  15. Original article

    Antibacterial activities and antioxidant capacity of Aloe vera

    The aim of this study was to identify, quantify, and compare the phytochemical contents, antioxidant capacities, and antibacterial activities of Aloe vera lyophilized leaf gel (LGE) and 95% ethanol leaf gel extra...

    Fatemeh Nejatzadeh-Barandozi

    Organic and Medicinal Chemistry Letters 2013 3:5

    Published on: 19 July 2013

  16. Original article

    Bioactive flavanoids from Glycosmis arborea

    Glycosmis is a genus of evergreen glabrous shrub and distributed all over India. It possesses various medicinal properties and is used in indigenous medicine for cough, rheumatism, anemia, and jaundice. Glycosmi...

    Mohammad Faheem Khan, Nisha Negi, Rajnikant Sharma and Devendra Singh Negi

    Organic and Medicinal Chemistry Letters 2013 3:4

    Published on: 4 March 2013

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