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  1. Content type: Original article

    Nanotechnology is now regarded as a distinct field of research in modern science and technology with multifaceted areas including biomedical applications. Among the various approaches currently available for t...

    Authors: Goutam Brahmachari, Sajal Sarkar, Ranjan Ghosh, Soma Barman, Narayan C Mandal, Shyamal K Jash, Bubun Banerjee and Rajiv Roy

    Citation: Organic and Medicinal Chemistry Letters 2014 4:18

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  2. Content type: Original article

    Aryl sulfides have significant importance from biological and pharmaceutical aspects. Transition metal-catalyzed carbon-sulfur cross-coupling reaction represents an important tool for the synthesis of sulfides...

    Authors: Debasish Sengupta and Basudeb Basu

    Citation: Organic and Medicinal Chemistry Letters 2014 4:17

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  3. Content type: Short communication

    1,8-Naphthyridine derivatives have attracted considerable attention because the 1,8-naphthyridine skeleton is present in many compounds that have been isolated from natural substances, with various biological ...

    Authors: Mallaiah Bucha, Laxminarayana Eppakayala, Thirumala Chary Maringanti, Giri Tharikoppula and Shashikala Kethireddy

    Citation: Organic and Medicinal Chemistry Letters 2014 4:16

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  4. Content type: Original article

    A rapid and sensitive ultraviolet-visible (UV-VIS) spectroscopic method was developed for the estimation of pyrimidine derivative 6-Bromo-3-(6-(2,6-dichlorophenyl)-2-(morpolinomethylamino) pyrimidine4-yl) -2H-...

    Authors: Anshu Chaudhary, Anoop Singh and Prabhakar Kumar Verma

    Citation: Organic and Medicinal Chemistry Letters 2014 4:15

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  5. Content type: Short communication

    Benzimidazoles and triazoles are useful structures for research and development of new pharmaceutical molecules and have received much attention in the last decade because of their highly potent medicinal acti...

    Authors: Karna Ji Harkala, Laxminarayana Eppakayala and Thirumala Chary Maringanti

    Citation: Organic and Medicinal Chemistry Letters 2014 4:14

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  6. Content type: Original article

    Macrotyloma uniflorum Linn (Fabaceae) is a herbaceous plant with annual branches. It is used in kidney stones, inflamed joints, fever, musculoskeletal disorders, sinus wounds and localized abdominal tumors. It is...

    Authors: Sneha Das, Neeru Vasudeva and Sunil Sharma

    Citation: Organic and Medicinal Chemistry Letters 2014 4:13

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  7. Content type: Short communication

    The current investigation sought to explore the nature of the secondary metabolites in the algae, Laurencia pacifica.

    Authors: Diana A Zaleta-Pinet, Ian P Holland, Mauricio Muñoz-Ochoa, J Ivan Murillo-Alvarez, Jennette A Sakoff, Ian A van Altena and Adam McCluskey

    Citation: Organic and Medicinal Chemistry Letters 2014 4:8

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  8. Content type: Short communication

    Azaheterocycles are an important class of compounds because of their highly potent medicinal activities, and the imidazole subcategory is of special interest in regard to drug discovery research.

    Authors: Debasish Bandyopadhyay, Lauren C Smith, Daniel R Garcia, Ram N Yadav and Bimal K Banik

    Citation: Organic and Medicinal Chemistry Letters 2014 4:9

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  9. Content type: Original article

    Leishmaniasis is a neglected tropical parasitic diseases affecting millions of people around the globe. Quinazolines are a group of compounds with diverse pharmacological activities. Owing to their promising a...

    Authors: Yihenew Simegniew Birhan, Adnan Ahmed Bekhit and Ariaya Hymete

    Citation: Organic and Medicinal Chemistry Letters 2014 4:10

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  10. Content type: Original article

    Malaria is an endemic disease affecting many countries in Tropical regions. In the search for compound hits for the design and/or development of new drugs against the disease, many research teams have resorted...

    Authors: Pascal Amoa Onguéné, Fidele Ntie-Kang, James Ajeck Mbah, Lydia Likowo Lifongo, Jean Claude Ndom, Wolfgang Sippl and Luc Meva′a Mbaze

    Citation: Organic and Medicinal Chemistry Letters 2014 4:6

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  11. Content type: Original article

    A series of 6-(substituted aldehyde)-3,4-dihydro-1-(tetrahydro-3,4-dihydroxy-5-(hydroxymethyl) furan-2-yl)-4-phenylpyrimidine-2(1H)-one derivative (6A-6P) was synthesized from the 6-(substituted aldehyde)-4-pheny...

    Authors: Rupesh Dudhe, Pramod Kumar Sharma and Prabhakar Kumar Verma

    Citation: Organic and Medicinal Chemistry Letters 2014 4:3

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  12. Content type: Original article

    The aim of the current investigation was to identify bioactive secondary metabolites including phenols, tannins, flavonoids, terpinedes, and steroids and compare the phytochemical analysis and antioxidant prof...

    Authors: Abdur Rauf, Ghias Uddin and Jawad Ali

    Citation: Organic and Medicinal Chemistry Letters 2014 4:5

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  13. Content type: Original article

    The aim of this study was to evaluate the effects of nitroxin biofertilizer and chemical fertilizer on the growth, yield, and essential oil composition of dill. The experiment was conducted under field conditi...

    Authors: Fatemeh Nejatzadeh-Barandozi and Fathollah Gholami-Borujeni

    Citation: Organic and Medicinal Chemistry Letters 2014 4:4

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  14. Content type: Original article

    Phenylazonaphtol-β-D-O-glycosides are alternative substrates for the detection of enzymatic activity of β-glycosidases which are involved in various important processes. These azoic compounds are currently exploi...

    Authors: Marco Brito-Arias, Carlos Aguilar-Lemus, Pamela B Hurtado-Ponce, Guadalupe Martínez-Barrón and Miguel Ibañez-Hernandez

    Citation: Organic and Medicinal Chemistry Letters 2014 4:2

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  15. Content type: Original article

    The level of expression of cannabinoid receptor type 2 (CB2R) in healthy and diseased brain has not been fully elucidated. Therefore, there is a growing interest to assess the regional expression of CB2R in the b...

    Authors: Rodrigo Teodoro, Rareş-Petru Moldovan, Corinna Lueg, Robert Günther, Cornelius K Donat, Friedrich-Alexander Ludwig, Steffen Fischer, Winnie Deuther-Conrad, Bernhard Wünsch and Peter Brust

    Citation: Organic and Medicinal Chemistry Letters 2013 3:11

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  16. Content type: Original article

    Drug metabolism and pharmacokinetic (DMPK) assessment has come to occupy a place of interest during the early stages of drug discovery today. Computer-based methods are slowly gaining ground in this area and a...

    Authors: Fidele Ntie-Kang, James A Mbah, Lydia L Lifongo, Luc C Owono Owono, Eugene Megnassan, Luc Meva'a Mbaze, Philip N Judson, Wolfgang Sippl and Simon MN Efange

    Citation: Organic and Medicinal Chemistry Letters 2013 3:10

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  17. Content type: Original article

    Pyrazole and pyrazolone motifs are well known for their wide range of biological activities such as antimicrobial, anti-inflammatory, and antitumor activities. The incorporation of more than one pharmacophore ...

    Authors: Poonam Khloya, Pawan Kumar, Arpana Mittal, Neeraj K Aggarwal and Pawan K Sharma

    Citation: Organic and Medicinal Chemistry Letters 2013 3:9

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  18. Content type: Original article

    Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are one of the key components in highly active anti-retroviral therapy because of their high specificity and less toxicity. NNRTIs inhibit reverse trans...

    Authors: Ashok Penta, Swastika Ganguly and Sankaran Murugesan

    Citation: Organic and Medicinal Chemistry Letters 2013 3:8

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    The Erratum to this article has been published in Organic and Medicinal Chemistry Letters 2013 3:12

  19. Content type: Original article

    We report the synthesis of benzimidazoles using lanthanum chloride as an efficient catalyst. One-pot synthesis of 2-substituted benzimidazole derivatives from o-phenylenediamine and a variety of aldehydes were de...

    Authors: Yekkirala Venkateswarlu, Sudhagani Ramesh Kumar and Panuganti Leelavathi

    Citation: Organic and Medicinal Chemistry Letters 2013 3:7

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  20. Content type: Original article

    Pyrazolones are traditionally synthesized by the reaction of β-keto esters with hydrazine and its derivatives. There are methods to synthesize β-keto esters from esters and aldehydes, but these methods have ma...

    Authors: Ramasamy Venkat Ragavan, Kalavathi Murugan Kumar, Vijayaparthasarathi Vijayakumar, Sundaramoorthy Sarveswari, Sudha Ramaiah, Anand Anbarasu, Sivashanmugam Karthikeyan, Periyasamy Giridharan and Nalilu Suchetha Kumari

    Citation: Organic and Medicinal Chemistry Letters 2013 3:6

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  21. Content type: Original article

    The aim of this study was to identify, quantify, and compare the phytochemical contents, antioxidant capacities, and antibacterial activities of Aloe vera lyophilized leaf gel (LGE) and 95% ethanol leaf gel extra...

    Authors: Fatemeh Nejatzadeh-Barandozi

    Citation: Organic and Medicinal Chemistry Letters 2013 3:5

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  22. Content type: Original article

    Glycosmis is a genus of evergreen glabrous shrub and distributed all over India. It possesses various medicinal properties and is used in indigenous medicine for cough, rheumatism, anemia, and jaundice. Glycosmi...

    Authors: Mohammad Faheem Khan, Nisha Negi, Rajnikant Sharma and Devendra Singh Negi

    Citation: Organic and Medicinal Chemistry Letters 2013 3:4

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