Organic and Medicinal Chemistry Letters

Table 2 IC ₅₀ of compounds 3a-l by MTT assay

From: Monastrol mimic Biginelli dihydropyrimidinone derivatives: synthesis, cytotoxicity screening against HepG2 and HeLa cell lines and molecular modeling study

Compound code	IC ₅₀ ^a(μg/mL)
	HepG2	HeLa
3a	180	216
3b	166	189
3c	207	240
3d	178	229
3e	194	-
3f	269	346
3 g	124	187
3 h	120	217
3i	218	374
3j	192	261
3 k	191	398
3 l	218	374

^a50% inhibitory concentration. HepG2, human hepatocellular carcinoma; HeLa, human epithelial carcinoma.

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