Organic and Medicinal Chemistry Letters

Table 8 Synthesis of β-keto esters by cross-Claisen condensation

From: β-Keto esters from ketones and ethyl chloroformate: a rapid, general, efficient synthesis of pyrazolones and their antimicrobial, in silico and in vitro cytotoxicity studies

Compound number	Ester	Product	Yield (%)
1			78
2			75
3			64
4			72
5			80
6			69
7			74
8			74
9			58
10			70
11			80
12			92
13			72
14			77
15			84
16			78
17			65^a
18			61
19			48
20			74
21			74
22			0^a
23			81
24			78
25			81
26			79
27			0^a

^aPercentage of products in crude LC-MS.

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