Scheme 5

Radiosynthesis and metabolism of [¹⁸F]17

Radiosynthesis and metabolism of [¹⁸ F]17. (a) Radiolabelling with K[¹⁸F]F-K_2.2.2-carbonate complex (5.6 mg, 15 μmol), 2 mg of 18, MeCN, 82°C, 10 min; (b) in vivo metabolism.